AbstractA new pathway via a cyclic intermediate for the synthesis of ketones from aldehydes and sulfonylhydrazone derivatives under basic conditions is proposed. Several control experiments were performed along with analysis of the mass spectra and in‐situ IR spectra of the reaction mixture. Inspired by the new mechanism, an efficient and scalable method for homologation of aldehydes to ketones was developed. A wide variety of target ketones were obtained in yields of 42–95 % by simply heating the 3‐(trifluoromethyl)benzene sulfonylhydrazones (3‐(Tfsyl)hydrazone) for 2 h at 110 °C with aldehydes and with K2CO3 and DMSO as base and solvent, respectively.

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