We propose an approach for modeling the pattern of the genetic diversity of microsatellite markers in a population with a mixed breeding strategy. Part of the population is reproduced sexually, and part is produced asexually. The method of the proposed simulation is different from others in that it produces a set of microsatellite markers as the outcome of a computer simulation of processes in a fixed-size population. These markers can be utilized with the assistance of available software to calculate various metrics of genetic diversity. Our approach is implemented in Python 3.10 and is accompanied by additional scripts that ensure result compatibility with programs that calculate different population characteristics.

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