Akihiro Kondo, Kazuhiro J. Fujimoto, Takeshi Yanai

A quantum chemical study on the anti-SARS-CoV-2 activity of TMPRSS2 inhibitors

  • Physical and Theoretical Chemistry
  • General Physics and Astronomy

Nafamostat and camostat are known to inhibit the spike protein-mediated fusion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by forming a covalent bond with the human transmembrane serine protease 2 (TMPRSS2) enzyme.

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