Rahul Srivastava, Hadi Raza, Pooja Kabra, Ashtha Arya, Athira Purushothaman, Pallavi A. Thomas

A Study to Assess Anti-Inflammatory Effect of Vitamin D on Gingivitis: A Dose Dependent Randomised Controlled Trial

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • Bioengineering
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • Bioengineering
Save to CiteDrive Show PDF

ABSTRACT Introduction: Vitamin D deficiency increases gingivitis risk. Studies show that higher vitamin D levels reduce inflammation. Materials and Methods: College conducted a double-blind, randomized, controlled trial on 451 people’s vitamin D and gingival health at baseline. For three months, participants were given a placebo (group A), 1000 international units (IU) of vitamin D3 per day (group B), 500 IU per day (group C), or 2000 IU per day (group A). Gingival scores were recorded for three months to assess the anti-inflammatory effect (the first, second, and third). Vitamin D levels also affected gingivitis. Results: Vitamin D dose-dependently reduces gingivitis inflammation. Vitamin D administration negatively correlated with gingival index score. Anti-inflammatory vitamin D levels are 32–37 ng/ml. Conclusion: Vitamin D supplementation can reduce gingivitis severity. The optimal blood vitamin D level is 30–35 ng/ml.

Need a simple solution for managing your BibTeX entries? Explore CiteDrive!

  • Web-based, modern reference management
  • Collaborate and share with fellow researchers
  • Integration with Overleaf
  • Comprehensive BibTeX/BibLaTeX support
  • Save articles and websites directly from your browser
  • Search for new articles from a database of tens of millions of references
Try out CiteDrive

More from our Archive