Neha Pathak, Anu R. I., Padmaj Kulkarni, Amol Patel

A Survey on Unmet Need for Uniform Next-Generation Sequencing Reporting in India

  • Oncology
  • Pediatrics, Perinatology and Child Health
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AbstractIntroduction: Next-generation sequencing (NGS) has paved the way for precision oncology in oncology clinics today. With rapidly advancing therapeutics, it is becoming increasingly important to obtain information about the molecular milieu of a patient's tumor. However, reporting and interpreting of NGS is fraught with complexity and variability. To understand the questions surrounding NGS reporting in India, we conducted a survey.Objectives: The aim of this study was to assess the gaps in NGS reporting and interpretation in Indian medical oncology clinics.Materials and Methods: An anonymized 10-question survey-based study among Indian medical oncologists through Google forms was conducted between October 4 and 8, 2022.Results: The sample size was n = 58. Seventy-one percent felt there was heterogeneity in NGS reporting, 72% were unaware of NGS reporting guidelines, and 62% did not feel the need for a molecular scientist assist in NGS interpretation. Almost all (98%) felt there was a need for uniform NGS reporting as well as an Indian NGS repository and data-sharing system (93%).Conclusion: Our survey highlights the need for a uniform national guideline concerning NGS reporting.

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