This study is intended to focus on the evaluation of posterior vertical mandibular asymmetry by calculating the mandibular asymmetry index on the panoramic radiography in different types of malocclusions, considering the sexual dimorphism in children and adolescent patients and performing a comparative analysis between these groups. In this context, a cross-sectional study was conducted for a group of 214 patients (134 females and 80 males with a mean age of 9.5 ± 2 years). The asymmetry index was calculated for each patient according to the Habets method. The results were analyzed by using the independent Student t-test, ANOVA and Mann–Whitney U-test at the 95% confidence level (p < 0.05). The results of the analyses showed a statistically significant difference between males and females at the level of the condylar index (p = 0.023) and a significant difference in the unilateral posterior crossbite in the Mann–Whitney U test (p = 0.01). No statistically significant differences were found between males and females in the index of the mandibular ramus and condyle-plus-ramus. The highest value of the asymmetry index was recorded at the level of the condyle. We found higher values of asymmetry in Angle Class I malocclusions in all groups and in Class II/1 in the group of females.

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