Kanniyan Binub, P.V. Harsha, Roshni S. Salim, Sobin Sunny, Pratibha Dabas, Swathy Chalil, Sneha Henry

An Observational Study on the Utility of Lab Parameters in Evaluating the Severity of Patients in South India with Covid-19

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • Bioengineering
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • Bioengineering
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ABSTRACT Laboratory testing has been extremely helpful in determining the severity and determining the course of treatment for COVID-19 patients. Our aim has been to look for variables of patient’s clinical and laboratory profile for two weeks and to observe their significance. Observational, Cross-sectional study. Data from the clinic and laboratory were compiled on Google form after informed consent from the patient. Statistical analysis was done using the Mann-Whitney U and unpaired t test. Population statistics included 202 patients (1st week) and 161 patients (2nd week), with the mean age of 61 ± 18 years. Most patients fell under the mild category (SPO2 >94%). High body mass index (n = 119) and hypertensive (n = 98) were the most common comorbidities observed. Diabetes, cardiovascular and respiratory diseases are the other comorbidities studied in this study. Hypoalbuminemia (n = 194) is the most deranged laboratory parameter in mild category, followed by lymphopenia (n = 109). In severe category also, hypoalbuminemia (n = 13) was deranged more. Other laboratory parameters included are CRP, D-Dimer, neutrophil and lymphocyte count. This study showed that albumin is a good predictor for estimating the severity of COVID-19 patients especially in the first week of their admission.

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