The high poverty rate is a strategic problem faced by North Sumatra Province. Poverty is still a serious problem; this is indicated by the large number of people who are still lacking in meeting their basic needs. This study aims to analyze the effect of economic growth, inflation and unemployment on poverty in the districts/cities of North Sumatra province. The research method used is quantitative research using times series data and cross section. This study uses multiple linear regression analysis. Based on the results of the panel data regression with the random effect model, it is known that economic growth does not affect poverty, but inflation and unemployment have a positive and significant effect on the poverty rate t sig unemployment (-4.382) and inflation (-4.984). Keywords: Economic Growth, Inflation, Unemployment, Poverty.

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