DOI: 10.4103/jpbs.jpbs_591_23 ISSN: 0976-4879

Antioxidant and Anti-Inflammatory Activity of the Ethanolic Extract of Euphorbia Hirta Leaf Extract: An In Vitro and In Silico Study

G Praveen, Kaliselvi Krishnamoorthy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • Bioengineering
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • Bioengineering
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BSTRACT

Objectives:

This study presents the antioxidant and anti-inflammatory activity of the ethanolic extract of Euphorbia hirta leaf extract.

Materials and Methods:

The antioxidant and anti-inflammatory activity of the extract was performed by in vitro assay. Our research employs a comprehensive approach combining experimental assays and computational simulations to assess the extract’s potential bioactive components and their interactions with key biomolecules.

Results:

The study’s results demonstrated a progressive rise in the percentage of inhibition, which was dependent on the dosage, in both antioxidant and anti-inflammatory activities. This trend was observed for both the extract and the standard, encompassing concentrations ranging from 100 to 500 μg/ml.

Conclusion:

The results showed that Euphorbia hirta’s possesses antioxidant and anti-inflammatory activity, and this may contribute to a traditional medicinal. The discoveries of this study contribute to a deeper understanding of Euphorbia hirta’s medicinal properties and its potential as a source of natural therapeutic agents.

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