Harsh Joshi, Vinod Sharma, B. L. Bairwa, Sanjeev Chopra, Ashok Gupta, Suresh Kumar Choudhary

ASSOCIATION OF HYPOCALCEMIA WITH MORTALITY AND MORBIDITY IN PATIENTS WITH MODERATE TO SEVERE TRAUMATIC BRAIN INJURY

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Background : The present study has been conducted to assess whether hypocalcemia can be used as a prognostic factor in the outcome of traumatic brain injury. Materials And Methods : This prospective study was done on 100 patients with moderate to severe traumatic brain injury. Serum calcium levels of patients had a Glasgow coma scale of 3–13 points following traumatic brain injury, with demonstrable intracranial lesions in cranial computed tomography were included. Student's t test, chi square test and Fisher's exact test were used for comparative analysis. Logistic regression and receiving operative curves analysis analysis were also done to assess the risk factors. Results: Statistically significant difference were found in the Ca2+levels on the 3rd day of admission between the patients with GOS ≤3 and the patients with GOS>3 (P=0.029).The best level of higher sensitivity (86.27%) and specificity (68.66%) of hypocalcaemia on 3rd 2+ day was the Ca2+ value of 1.14 mmol/L. Conclusion: The serum Ca levels on day 3 could be useful for the prediction of mortality and disability in patients with moderate to severe traumatic brain injury.

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