Central and peripheral contrast sensitivity in thyroid eye disease
Kasturi Bhattacharjee, Obaidur Rehman, Parul Ichhpujani, Vatsalya Venkatraman- Ophthalmology
Purpose:
Assessment of central and peripheral contrast sensitivity (CS) in thyroid eye disease (TED) with and without dysthyroid optic neuropathy (DON).
Methods:
This cross-sectional study enrolled 33 eyes of 18 treatment-naïve TED patients and 18 age- and sex-matched healthy controls for comparative analysis. A detailed ophthalmic examination included visual acuity (VA), intraocular pressure measurement, slit-lamp biomicroscopy, and CS testing (central and four peripheral regions) using Spaeth–Richman Contrast Sensitivity test was done.
Results:
The average age of TED patients was 47.17 ± 13.99 years and a female preponderance was noted (66.66%,
Conclusion:
Visual function compromise can be detected in TED in the presence of intact VA, by testing CS. Peripheral CS deteriorates with increasing inflammation and in DON. Serial monitoring of both central and peripheral CS may help in diagnosing DON early.