Characterization of Vestibular Perception in Patients with Persistent Postural-Perceptual Dizziness
Megan J. Kobel, Andrew R. Wagner, John G. Oas, Daniel M. Merfeld- Neurology (clinical)
- Sensory Systems
- Otorhinolaryngology
Objective
To assess vestibular (i.e., passive self-motion) perception in patients diagnosed with persistent postural-perceptual dizziness (PPPD).
Study Design
Case-controlled, cross-sectional, observational investigation.
Setting
Single-center laboratory-based study.
Patients
Thirteen patients with PPPD, 13 age-matched healthy control volunteers. Of those with PPPD, eight had co-occurring vestibular migraine (VM).
Interventions
All participants completed a vestibular threshold test battery reflecting perception with predominant inputs from (
Main Outcome Measures
Direction-recognition thresholds for each vestibular threshold test condition.
Results
Across all patients with PPPD, higher thresholds for superior-inferior
Conclusions
Patients with PPPD did not display a global worsening of passive self-motion perception as quantified by vestibular perceptual thresholds. Instead, patients with PPPD displayed elevated thresholds for only roll tilt and