DOI: 10.1200/op.23.00594 ISSN: 2688-1527

Comprehensive Recommendations for the Clinical Management of Pregnant Women With Noninvasive Prenatal Test Results Suspicious of a Maternal Malignancy

Catharina J. Heesterbeek, Liesbeth Lenaerts, Vivianne C.G. Tjan-Heijnen, Frédéric Amant, Maartje C. van Rij, Miel Theunis, Christine E.M. de Die-Smulders, Joris R. Vermeesch, Merryn V.E. Macville,
  • Oncology (nursing)
  • Health Policy
  • Oncology

In this article, we defined comprehensive recommendations for the clinical follow-up of pregnant women with a malignancy-suspicious NIPT result, on the basis of the vast experience with population-based NIPT screening programs in two European countries complemented with published large data sets. These recommendations provide a tool for classifying NIPT results as malignancy-suspicious, and guide health care professionals in structured clinical decision making for the diagnostic process of pregnant women who receive such a malignancy-suspicious NIPT result.

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