Total knee arthroplasty (TKA) is a popular treatment for end-stage knee osteoarthritis. Advances in understanding knee biomechanics have led to the development of medial pivot (MP) prostheses, which aim to replicate natural knee kinematics. While short- and mid-term studies have shown favorable outcomes for MP-TKA, long-term follow-up studies are limited. This systematic review aims to analyze the available evidence on long-term outcomes of MP-TKA, including survivorship, complications, and patient-reported outcome measures (PROMs). A comprehensive search was conducted in PubMed, Embase, and Cochrane Database of Systematic Reviews for English language studies reporting long-term outcomes of primary MP-TKA. Nine studies with an average follow-up of 12.4 years were included. Data on survivorship, complications, and PROMs were collected and analyzed. The overall survivorship of MP-TKA was 98.2% at an average follow-up of 12.4 years. Aseptic loosening and periprosthetic joint infection (PJI) were the most common reasons for revision, with a revision rate of 0.4% for each. The overall complication rate was 6.6%, with secondary anterior knee pain and PJI being the most frequent complications. The reoperation rate was 3.1%, primarily due to PJI and knee instability. PROMs significantly improved postoperatively. MP-TKA demonstrates favorable long-term outcomes with high survivorship, low complication rates, and enhanced PROMs. The procedure provides reliable management for end-stage osteoarthritis, offering patients improved knee function and pain relief. Further research with standardized reporting and larger sample sizes is needed to validate and compare these findings to other implant designs.

More from our Archive

• DOI: 10.3390/prosthesis5030046 2023

  Human Walking Gait Classification Utilizing an Artificial Neural Network for the Ergonomics Study of Lower Limb Prosthetics

  Farika Tono Putri, Wahyu Caesarendra, Grzegorz Królczyk, Adam Glowacz, Hartanto Prawibowo, Rifky Ismail, Ragil Tri Indrawati

• DOI: 10.3390/prosthesis5030043 2023

  Clinical, Radiological, and Aesthetic Outcomes after Placement of a Bioactive-Surfaced Implant with Immediate or Delayed Loading in the Anterior Maxilla: 1-Year Retrospective Follow-Up Study

  Roberta Iacono, Yaniv Mayer, Gaetano Marenzi, Balan Vitor Ferreira, Godoy Eduardo Pires, Marco Migliorati, Francesco Bagnasco

• DOI: 10.1002/pmrj.13039 2023

  Effects of mobility dose on discharge disposition in critically ill stroke patients

  Nicole Mazwi, India Lissak, Karuna Wongtangman, Katharina Platzbecker, Lea Albrecht, Bijan Teja, Xinling Xu, Nicole M. Morteo, Tawnee Sparling, Nicola Latronico, Silvia Barbieri, Manfred Blobner, Stefan J. Schaller, Matthias Eikermann

• DOI: 10.1093/jbcr/irad106 2023

  Tripterine Inhibits Proliferation and Promotes Apoptosis of Keloid Fibroblasts by Targeting ROS/JNK Signaling

  Fang Huang, Enjing Zhang, Yan Lei, Qiong Yan, Chengbin Xue

• DOI: 10.1177/02692155231185446 2023

  Physical functioning factors predicting a return home after stroke rehabilitation: A systematic review and meta-analysis

  Odile Chevalley, Steven Truijen, Emmanuelle Opsommer, Wim Saeys

• DOI: 10.1097/phm.0000000000002312 2023

  An updated systematic review and quantitative synthesis of physical activity levels in multiple sclerosis

  Brenda Jeng, Noah G. DuBose, Trevor B. Martin, Petra Šilić, Victoria A. Flores, Peixuan Zheng, Robert W. Motl

• DOI: 10.1093/humrep/dead136 2023

  The destinies of human embryos reaching blastocyst stage between Day 4 and Day 7 diverge as early as fertilization

  Giovanni Coticchio, Kenji Ezoe, Cristina Lagalla, Carlotta Zacà, Andrea Borini, Keiichi Kato

• DOI: 10.1002/pmrj.13038 2023

  Factors associated with pain pressure threshold in both local and remote sites in knee osteoarthritis

  Marta Imamura, Ingrid Rebello‐Sanchez, Joao Parente, Anna Marduy, Karen Vasquez‐Avila, Kevin Pacheco‐Barrios, Luis Castelo‐Branco, Marcel Simis, Linamara Battistella, Felipe Fregni

• DOI: 10.1093/jbcr/irad107 2023

  Augmented Renal Function in Burn Patients: Occurrence and Discordance With Commonly Used Methods to Assess Renal Function

  Scott W Mueller, Brittany Blass, Kyle C Molina, Cameron Gibson, Martin Krsak, Amber D Kohler, Lyndsay Deeter, Jennifer Stalilonis, Arek J Wiktor

• DOI: 10.3390/prosthesis5030044 2023

  Long-Term Follow-Up of Medial Pivot Total Knee Arthroplasty: A Systematic Review of the Current Evidence

  Giorgio Cacciola, Fortunato Giustra, Francesco Bosco, Luigi Sabatini, Salvatore Risitano, Federico De Meo, Lorenzo Braconi, Pietro Cavaliere, Alessandro Massè, Giuseppe Solarino