DOI: 10.1002/ajoc.202400056 ISSN: 2193-5807
Manganese catalyzed oxidative coupling of aromatic diamines and alcohols with aminoxyl radicals in the synthesis of benzimidazoles
Hui Han, Zhen-Jiang Xu, Limin Wang, Jian-wei Han- Organic Chemistry
We herein report a solvent‐free, oxidative coupling reaction of alcohols with aromatic diamines in air. 9‐Azabicyclo[3.3.1]nonan‐N‐oxyl (ABNO) in combination with a manganese(II) catalyst, serves to effectively promote the reaction, leading to the selective synthesis of 2‐substituted benzimidazoles and 1,2‐disubstituted benzimidazoles.