Retrospective evaluation of the improvement in the urinary status‐related quality of life after robot‐assisted radical prostatectomy
Yuki Kohada, Keisuke Hieda, Shunsuke Miyamoto, Ryo Tasaka, Akihiro Asami, Kosuke Akiyama, Yuki Sakamoto, Fumiaki Kirishima, Kohei Saito, Takafumi Fukushima, Kenshiro Takemoto, Takashi Babasaki, Kohei Kobatake, Hiroyuki Kitano, Keisuke Goto, Kenichiro Ikeda, Tetsutaro Hayashi, Nobuyuki Hinata- Urology
Objectives
This study aimed to investigate the characteristics of patients who report improvement in quality of life (QOL) related to urinary status after undergoing robot‐assisted radical prostatectomy (RARP) for localized prostate cancer.
Methods
We retrospectively reviewed the patients who underwent RARP between May 2010 and May 2021 at our institution and were preoperatively unsatisfied with their urinary status. Patients were grouped as Group 1 (improved patients: “satisfied” with urinary status based on international prostate symptom score QOL [IPSS‐QOL] = 0–2 at 12 months after RARP) and Group 2 (unimproved group: “unsatisfied”–IPSS‐QOL 3–6). Additionally, the Expanded Prostate Cancer Index Composite (EPIC) urinary subdomains (urinary function, urinary bother [UB], urinary incontinence, and urinary irritation/obstruction [UIR]) and IPSS were evaluated preoperatively and till 12 months after RARP.
Results
Of the 237 patients, 72 (30.4%) were Group 1, and 165 (69.6%) were Group 2. Only UB and UIR improved at 12 months after RARP in Group 1, while other EPIC urinary subdomains remained unimproved at 12 months in both groups. On the other hand, IPSS improved at 12 months in both groups. Univariate and multivariate analysis revealed that the nerve‐sparing, preoperative low IPSS (<11 vs. ≥11), and low IPSS‐QOL (3 vs. 4–6) were associated with improvement in urinary status‐related QOL (p < 0.05).
Conclusions
Improvement in UB and UIR are important factors to ascertain improvement in urinary status‐related QOL after RARP. Nerve‐sparing and preoperative IPSS/IPSS‐QOL values are useful predictors of this improvement.