Jaime L. Jensen, Rajeshwer S. Sankhala, Vincent Dussupt, Hongjun Bai, Agnes Hajduczki, Kerri G. Lal, William C. Chang, Elizabeth J. Martinez, Caroline E. Peterson, Emily S. Golub, Phyllis A. Rees, Letzibeth Mendez-Rivera, Michelle Zemil, Erin Kavusak, Sandra V. Mayer, Lindsay Wieczorek, Shruthi Kannan, Benjamin J. Doranz, Edgar Davidson, Eun Sung Yang, Yi Zhang, Man Chen, Misook Choe, Lingshu Wang, Gregory D. Gromowski, Richard A. Koup, Nelson L. Michael, Victoria R. Polonis, Morgane Rolland, Kayvon Modjarrad, Shelly J. Krebs, M. Gordon Joyce

Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity

  • Virology
  • Insect Science
  • Immunology
  • Microbiology

Characterization of MAbs against SARS-CoV-2, elicited through vaccination or natural infection, has provided vital immunotherapeutic options for curbing the COVID-19 pandemic and has supplied critical insights into SARS-CoV-2 escape, transmissibility, and mechanisms of viral inactivation. Neutralizing MAbs that target the RBD but do not block ACE2 binding are of particular interest because the epitopes are well conserved within sarbecoviruses and MAbs targeting this area demonstrate cross-reactivity.

Need a simple solution for managing your BibTeX entries? Explore CiteDrive!

  • Web-based, modern reference management
  • Collaborate and share with fellow researchers
  • Integration with Overleaf
  • Comprehensive BibTeX/BibLaTeX support
  • Save articles and websites directly from your browser
  • Search for new articles from a database of tens of millions of references
Try out CiteDrive

More from our Archive