DOI: 10.1097/bor.0000000000000957 ISSN: 1040-8711
Update on autoantibodies and related biomarkers in autoimmune inflammatory myopathies
May Y. Choi, Minoru Satoh, Marvin J. Fritzler- Rheumatology
Purpose of review
This manuscript reviews recently published advances in the identification of autoimmune inflammatory myopathies (AIM)-specific and AIM-related autoantibodies considered of value in the workup of patients suspected of having AIM. Newer autoantibodies, developments, and advances in the methodology of testing, the gaps and pitfalls in using these assays as diagnostic biomarkers, and the importance of considering overlap diseases and unique clinical AIM phenotypes are discussed.
Recent findings
Summary
The spectrum of autoantibodies and related biomarkers in AIM continues to expand. Many of these have clear clinical implications in regard to subsets and overlap conditions of AIM, associated malignancy and pathological findings.